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👄 Máculas pigmentadas periorais na Síndrome de Peutz-Jeghers ⠀ A presença de máculas escuras ao redor da boca, mucosa oral, mãos e pés é um sinal característico da Síndrome de Peutz-Jeghers, uma síndrome genética rara e autossômica dominante. ⠀ 🧬 O que é a SPJ? É uma condição causada por mutações no gene STK11, e se manifesta com: • Máculas melanóticas • Pólipos hamartomatosos no trato gastrointestinal • Aumento do risco de câncer em vários órgãos (intestino
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