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💊 Glibenclamida vs Gliclazida: ambas são sulfonilureias → estimulam insulina 🧪 e podem causar hipoglicemia ⚠️; usadas no DM2 quando dieta/exercício/metformina não bastam 📉. Diferenças: Glibenclamida = mais potente ⏱️ longa ação, ↑ risco de hipo e ganho de peso ⚠️; Gliclazida = ação moderada, mais segura 👍, menor risco . 👵 Perfil: evitar glibenclamida em idosos/renal; gliclazida é preferida.
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