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O Odefsey é um comprimido de dose única diária usado no tratamento do HIV-1. Ele combina três antirretrovirais: emtricitabina, rilpivirina e tenofovir alafenamida . Foi aprovado nos EUA e na Europa em 2016, ou seja, já está há quase 10 anos disponível no exterior. No Brasil, o esquema padrão mais utilizado no SUS combina tenofovir DF, lamivudina e dolutegravir, mas em dois comprimidos separados. A principal diferença é que o Odefsey utiliza rilpivirina no lugar do dolutegravir e um tipo ma
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