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Os anti-inflamatórios mais comuns, como ibuprofeno, diclofenaco, naproxeno e cetoprofeno, atuam bloqueando enzimas chamadas COX-1 e COX-2. Essas enzimas são responsáveis pela produção das prostaglandinas, substâncias que participam da inflamação, da dor e da febre. Quando você reduz a produção de prostaglandinas, a dor e a inflamação diminuem, mas o organismo também perde várias funções protetoras importantes. Um dos principais problemas é que as prostaglandinas protegem o estômago. Elas estimu
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