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Ter o endométrio fino pode dificultar a gravidez, pois o embrião irá se desenvolver a partir dos substratos desta camada interna do útero, considerada a mais importante para a reprodução. Nesse sentido, quanto mais fino for o endométrio, mais dificuldade a paciente vai ter para engravidar. Um endométrio com espessura adequada deve ter, no mínimo 7 milímetros e, no máximo, de 12 a 14 milímetros .
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