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Paroxetina funciona mesmo? A paroxetina é um antidepressivo da classe dos inibidores seletivos da recaptação de serotonina e está entre os mais antigos e estudados do mercado. Mas ela ainda funciona nos dias de hoje? A resposta é: sim, desde que bem indicada. A paroxetina é eficaz no tratamento de: - Transtorno depressivo maior - Transtornos de ansiedade - TOC e TEPT Mas é um fármaco que exige cautela: - Pode ter maior taxa de efeitos colaterais iniciais
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A vortioxetina é um antidepressivo de nova geração, aprovada para o tratamento do transtorno depressivo maior. Seu mecanismo é multimodal: além de inibir a recaptação de serotonina, ela atua em vários subtipos de receptores serotoninérgicos, o que pode explicar seus efeitos em cognição, humor e ansiedade. Estudos mostram que a vortioxetina pode: ✔ Reduzir sintomas depressivos com boa tolerabilidade ✔ Melhorar sintomas cognitivos associados à depressão ✔ Ter menos impacto sobre função sexual
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