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O roacutan é um medicamento à base de isotretinoína, amplamente utilizado no tratamento da acne severa e resistente a outras terapias. Seu mecanismo de ação envolve a redução da produção sebácea, a inibição da proliferação de Propionibacterium acnes e efeitos anti-inflamatórios na pele. Embora sua bula descreva diversos efeitos adversos, na prática clínica, os principais pontos de atenção são seu potencial teratogênico em mulheres, o aumento das transaminases hepáticas e as alterações
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