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Tiga bulan pertama kehamilan adalah periode pembentukan struktur organ utama dan diferensiasi berbagai jaringan. Selama periode ini, setiap tahap perkembangan mudah terganggu oleh datangnya faktor teratogenik, sehingga tahap awal kehamilan adalah insiden tinggi kelainan bentuk selama seluruh proses perkembangan embrio. Pada 50g minggu pertama pembuahan, umumnya diyakini bahwa teratogen memainkan efek "semua atau tidak sama sekali" pada embrio pada periode ini. Dengan kata lain, selama periode i...
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